Details of the Drug

General Information of Drug (ID: DMSUZFO)

Drug Name

NH-4

Synonyms

ammonium; Ammonium ion; Ammonium(1+); azanium; NH4+; Ammonium cation; 14798-03-9; Ammonia ion; Ammonium ion(+); AMMONIUM CATION WITH D; UNII-54S68520I4; NH4(+); 54S68520I4; Ammonium Compounds; ND4; Quaternary ammonium compounds; Nitrogen cation; Ammonium(+); nitrogen(1+); Nitrogen tetrahydride; Ammonium ion(1+); Ammonium (NH4+); AC1NUTFY; AC1NUTFO; Ammonia ion (NH4+); Ammonium ion (NH4+); nitrogen(1+) trihydride; Ammonium (8CI,9CI); Ammonia, ion (NH41+); AC1Q1W88; AC1L18R7; DTXSID5043974; CHEBI:29352; CHEBI:28938; CTK0H5427

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

#Ro5 Violations (Lipinski): 0

Molecular Weight (mw)

18.039

Topological Polar Surface Area (xlogp)

-0.7

Rotatable Bond Count (rotbonds)

0

Hydrogen Bond Donor Count (hbonddonor)

1

Hydrogen Bond Acceptor Count (hbondacc)

0

Chemical Identifiers

Formula: H4N+
IUPAC Name: azanium
Canonical SMILES: [NH4+]
InChI: InChI=1S/H3N/h1H3/p+1
InChIKey: QGZKDVFQNNGYKY-UHFFFAOYSA-O

Cross-matching ID

PubChem CID: 223
ChEBI ID: CHEBI:28938
CAS Number: 14798-03-9
TTD ID: D0E2IR

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Thyroid hormone receptor (THR)	TTQWUPT	NOUNIPROTAC	Antagonist	[1]

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Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	Design of thyroid hormone receptor antagonists from first principles. J Steroid Biochem Mol Biol. 2002 Dec;83(1-5):59-73.
2	Sobetirome: a case history of bench-to-clinic drug discovery and development. Heart Fail Rev. 2010 Mar;15(2):177-82.
3	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.